Thrombopoietin Receptor Agonist Use in Children_ Data From the Pediatric ITP Consortium of North America ICON2 Study
The purpose of this multicenter retrospective study was to understand the off-label use of the thrombopoietin-receptor agonists in pediatric patients with ITP. Neunert C, Despotovic J, Haley K, et al. Thrombopoietin Receptor Agonist Use in Children: Data from the Pediatric ITP Consortium of North America ICON2 Study. Pediatr Blood Cancer 2016 Aug; 63(8): 1407-13.
Pediatric hematologists from North America (n=278) were surveyed about their counseling to families about sports participation in children with ITP. Kumar M, Lambert MP, Breakey V, et al. Sports Participation in Children and Adolescents with Immune Thrombocytopenia (ITP). Pediatr Blood Cancer 2015 Dec; 62(12): 2223-5.
Second‐line treatments in children with immune thrombocytopenia_ Effect on platelet count and patient‐centered outcomes
A prospective, multi-center, observational study of 120 children starting second-line treatments for ITP compared treatment outcomes including platelet count, bleeding, and HRQoL utilizing the Kids ITP Tool (KIT). Grace RF, Shimano KA, Bhat R, et al. Second-line treatments in children with immune thrombocytopenia: Effect on platelet count and patient-centered outcomes. Am J Hematol. 2019 Jul;94(7):741-750.
Physician decision making in selection of second‐line treatments in immune thrombocytopenia in children
This prospective, observational, longitudinal cohort study of 120 children with ITP from 21 ICON centers examined physician treatment decisions in selecting specific second line agents in ITP. Grace RF, Despotovic JM, Bennett CM, et al. Physician decision making in selection of second-line treatments in immune thrombocytopenia in children. Am J Hematol 2018 Jul; 93(7):882-888.
Association of a positive direct antiglobulin test with chronic immune thrombocytopenia and use of second line therapies in children_ A multi‐institutional review
A multi-institutional retrospective review of 311 pediatric patients with ITP identified clinical characteristics associated with disease course. Kim TO, Grimes AB, Kirk S, et al. Association of a positive direct antiglobulin test with chronic immune thrombocytopenia and use of second line therapies in children: A multi-institutional review. Am J Hematol. 2019 Apr;94(4):461-466.